Over 800,000 people die annually as a result of overloaded work schedules

South Korean scientists conducted an MRI (Magnetic Resonance Imaging) study involving 110 healthcare workers and discovered that structural changes occur in the brains of people working 52 or more hours per week. These changes were most noticeable in regions responsible for executive functions and emotional regulation.

Workers experiencing overload showed a 19% greater volume in the left middle frontal gyrus compared to those with standard work schedules. This gyrus is associated with cognitive functions. Additionally, changes were recorded in the insular cortex and superior temporal gyrus, which play important roles in working memory, problem-solving, and emotional management.

Researchers suggest that the increase in brain volume may be a neuroadaptive response to chronic stress, although the exact mechanisms remain unclear. Prolonged overwork can disrupt sleep patterns, which activates the stress response and increases the risk of anxiety and depression. Chronic stress and insufficient recovery alter brain morphology and connections, leading to cognitive and emotional disorders. According to International Labour Organization estimates, more than 800,000 people die each year as a result of excessively long working hours.

Scientists emphasize that these are preliminary conclusions, and long-term studies are necessary to determine whether these changes can be reversed by reducing workload. The study, published in Occupational & Environmental Medicine, demonstrates that overwork should be considered a critical health issue. Policies are recommended to limit extreme working hours.

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